Compared to the year before the procedure, at 1-year postadenotonsillectomy follow-up, there was a % reduction in acute asthma exacerbations and a % reduction in acute status asthmaticus ( P < for both). [ 68 , 69 ] In addition, asthma-related emergency department visits were reduced by % and asthma-related hospitalizations by %. Patients who underwent the procedure also had significantly fewer refills of several asthma medications. In contrast, no significant reductions were observed in any of these outcomes among children who did not undergo adenotonsillectomy. [ 68 , 69 ]
Studies on corticosteroids tend to lean toward the extreme use, rather than the average use. For example, some studies look at corticosteroids for extreme and rarer cases of eczema. This makes it harder to research what long-term studies are out there on steroid use. To complicate things further, corticosteroids can be oral, topical, injected, or inhaled, and this dramatically changes the benefits and risks, and in turn the short-term and long-term effects. Speak with your doctor and pharmacist on what, if any, long-term studies out there are relevant to your own medical treatment.
The most common side effect of topical corticosteroid use is skin atrophy. All topical steroids can induce atrophy, but higher potency steroids, occlusion, thinner skin, and older patient age increase the risk. The face, the backs of the hands, and intertriginous areas are particularly susceptible. Resolution often occurs after discontinuing use of these agents, but it may take months. Concurrent use of topical tretinoin (Retin-A) % may reduce the incidence of atrophy from chronic steroid applications. 30 Other side effects from topical steroids include permanent dermal atrophy, telangiectasia, and striae.