Effects of steroids on bone tissue and marrow

In addition to the mentioned side effects several others have been reported. In both males and females acne are frequently reported, as well as hypertrophy of sebaceous glands, increased tallow excretion, hair loss, and alopecia. There is some evidence that anabolic steroid abuse may affect the immune system, leading to a decreased effectiveness of the defense system. Steroid use decreases the glucose tolerance, while there is an increase in insulin resistance. These changes mimic Type II diabetes. These changes seem to be reversible after abstention from the drugs.

References:
American Medical Association, Council on Scientific Affairs. Medical and non-medical uses of anabolic-androgenic steroids. J. Amer. Med. Assoc. 264: 2923-2927, 1990.
Bahrke, ., . Yesalosk, and . Wright. Psychological and behavioural effects of endogenous testosterone levels and anabolic-androgenic steroids among males: a review. Sports Med. 10: 303-337, 1990.
Buckley, ., . Yasalis, . Friedl, . Anderson, . Streit, and . Wright. Estimated prevalance of anabolic steroid use among male high school seniors. J. Amer. Med. Assoc. 260: 3441-3445, 1988.
Rogozkin, V. Metabolism of Anabolic Androgenic Steroids. Leningrad: Nauka, 1988.
United States Olympic Committee. USOC Drug Education Handbook. Colorado Springs: USOC, 1989.
Assessment of Aggressive Behavior and Plasma Testosterone in a Young Criminal PopulationLeo E. Kreuz, MD, MAJ, MCand Robert M. Rose, MD, June 23, 1971. Revision received December 1, 1971. 1972 American Psychosomatic Society
BEHRE, ., K. ABSHAGEN, M. OETTEL, D. HUBLER AND E. NIESCHLAG. Intramuscular injection of testosterone undecanoate for the treatment of male hypogonadism: phase I studies. Eur J Endocrinol 140:414 ***8211; 419. 1999

Scientists have attempted to test the association between anabolic steroids and aggression by administering high steroid doses or placebo for days or weeks to human volunteers and then asking the people to report on their behavioral symptoms. To date, four such studies have been conducted. In three, high steroid doses did produce greater feelings of irritability and aggression than did placebo, although the effects appear to be highly variable across individuals. In one study, the drugs did not have that effect. One possible explanation, according to the researchers, is that some but not all anabolic steroids increase irritability and aggression. Recent animal studies show an increase in aggression after steroid administration.

MedShadow would like to change the conversation, both public and private, over anabolic steroids  to include a very basic question.  What are the long term effects of taking steroids , and how does this weigh against the short term effects?   How does age effect the long-term effects, are adolescents at greater risk for negative long-term effects?   Anabolic steroids are popular, despite being “banned” or “illegal”, and it is important to learn more about the safety and long-term consequences before making a short-term decision.

Effects of steroids on bone tissue and marrow

effects of steroids on bone tissue and marrow

MedShadow would like to change the conversation, both public and private, over anabolic steroids  to include a very basic question.  What are the long term effects of taking steroids , and how does this weigh against the short term effects?   How does age effect the long-term effects, are adolescents at greater risk for negative long-term effects?   Anabolic steroids are popular, despite being “banned” or “illegal”, and it is important to learn more about the safety and long-term consequences before making a short-term decision.

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