Mometasone is a synthetic (man-made) glucocorticoid (steroid) that is used on the skin to relieve itching and inflammation of eczema , dermatitis , allergy and other skin rashes. The naturally-occurring glucocorticoid is cortisol or hydrocortisone which is produced in the body by the adrenal glands. Drugs within the same class as mometasone include betamethasone dipropionate (Diprosone), triamcinolone (Aristocort), diflorasone diacetate (Florone), and others. Application of glucocorticoids such as mometasone to the skin may suppress the body's own production of cortisol by the adrenal glands; however mometasone and others within its class are considered intermediate in potency and are less likely to have this effect as compared to highly potent glucocorticoids. Mometasone works by suppressing inflammation and the immune response associated with inflammation. Mometasone was approved by the FDA in 1987.