When to worry:
Anaphylaxis is an emergency and must be seen immediately by a vet. Often the reaction occurs in the vet clinic (sometimes within seconds of vaccination) or soon after the animal has left the clinic, although it can take up to 24 hours to manifest (so you should keep a close eye on the animal at home). The vet will usually rush the dog straight out to a treatment room, where it will receive oxygen, IV fluids, anti-histamines, adrenaline, anti-inflammatories and sometimes other drugs to aid in the treating of low blood pressure.
Controlled clinical studies have shown that intranasal corticosteroids may cause a reduction in growth velocity in pediatric patients. This effect has been observed in the absence of laboratory evidence of HPA axis suppression, suggesting that growth velocity is a more sensitive indicator of systemic corticosteroid exposure in pediatric patients than some commonly used tests of HPA axis function. The long-term effects of this reduction in growth velocity associated with intranasal corticosteroids, including the impact on final adult height, are unknown. The potential for “catch-up” growth following discontinuation of treatment with intranasal corticosteroids has not been adequately studied. The growth of pediatric patients receiving intranasal corticosteroids, including DYMISTA, should be monitored routinely (., via stadiometry). The potential growth effects of prolonged treatment should be weighed against the clinical benefits obtained and the risks/benefits of treatment alternatives.