The use of Stanozolol will suppress natural testosterone production in all men and should only be used in conjunction with exogenous testosterone. Failure to supplement with exogenous testosterone will put the man into a low testosterone state. The form of testosterone is inconsequential.
Once all Stanozolol use is ended and any and all anabolic steroids have cleared the body natural testosterone production will begin again. It will not occur overnight and it is recommended that a Post Cycle Therapy (PCT) plan follow use. A PCT plan will aid in recovery. A PCT plan will not complete recovery, this will still take several months, but it will speed up the process and increase the odds of a successful recovery.
Important Note: Women do not need to supplement with testosterone during Stanozolol use.
Important Note: Natural testosterone recovery assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) during use and that no prior low testosterone condition existed prior to use.
Metabolic effects occurring during anabolic steroid therapy in immobilized patients or those with metastatic breast disease include osteolytic-induced hypercalcemia.
Anabolic steroids effect electrolyte balance, nitrogen retention, and urinary calcium excretion. Edema, with and without congestive heart failure, has occurred during anabolic steroid therapy.
The androgenic activity of anabolic steroids may decrease levels of thyroxin-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction.
Significant increases in low density lipoproteins (LDL) and decreases in high density lipoproteins (HDL) have occurred. [ Ref ]
Of concern to any user of Winstrol during a cycle should be its intoxicating effect on the liver . The drug is a 17aa structured steroid , meaning it has been structured in a way which allows it to be orally bio-available, yet this has the negative effect of making Winstrol potentially harmful to the liver. It is therefore paramount the duration of a Winstrol cycle is limited, the dose of the drug is not excessive, the user does not stack it with other hepatotoxic compounds, does not drink alcohol whilst on cycle, and does not use Winstrol if they have an underlying medical condition which effects the livers health. There are supplements available which also help protect the liver (Milk Thistle, Liv-52 etc), and these would be advisable during any Winstrol cycle .