Sex hormone-binding globulin (SHBG) is thought to mainly function as a transporter and reservoir for the estradiol and testosterone sex hormones. However it has also been demonstrated that SHBG can bind to a cell surface receptor (SHBG-R). The SHBG-R has not been completely characterized. A subset of steroids are able to bind to the SHBG/SHBG-R complex resulting in an activation of adenylyl cyclase and synthesis of the cAMP second messenger.  Hence the SHBG/SHBG-R complex appears to act as a transmembrane steroid receptor that is capable of transmitting signals to the interior of cells.
The most commonly used among the three types of steroids is the anabolic steroid. This is used by men to enhance their muscles, thus, increasing their physical appearance. There are negative reviews associated with the use of steroid. However, if the proper dosing and route are followed, surely it will do general good in the body. It is the abuse of the one taking the medication which is responsible in creating the ill effect of the drug. There are various lists of steroids that are recommended to use by the patient. All you have to do is to select the one that will work for you. The overall benefits of the drug can cover the negative effects. It is not only the steroids that have adverse effect; almost every drug has side effects mentioned in the drug literature. The main principle is that, take the steroids that are generally safe, effective, and with fewer side effects mentioned. Always refer to the drug literature to ensure proper handling and safety of the one using the medication.